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Fabomotizole is an anxiolytic drug developed in the beginning of 2000s by the Russian Academy of Medical Sciences. It is currently available commercially under the trade name of Afobazole.
The goal of researchers at that time was to create a selective anxiolytic agent that would not have the adverse effects of benzodiazepines. In the open studies, the drug appeared to be as effective for the treatment of generalised anxiety disorder as diazepam, while causing significantly fewer side effects.
The producers of Afobazole claim that it stabilizes and upregulates GABA and benzodizepame receptors, exhibits neuroprotective properties, and diminishes anxiety and tensions in the body. The drug is designed above all for people with asthenic personal traits such as emotianal lability, e.g. tendency to react emotionally to stressful situations.
Fabomotizole is used in Russia to treat the following symptoms:
- Generalized anxiety disorder symptoms, e.g. bad feelings, tensions in the body, irritability, tearfulness, fearfulness, etc.
- Various somatic (psycophysiological) disorders, e.g. asthma, irritable bowel syndrome, systemic lupus erythematosus, ishemic heart diseases, etc.
- Sleep disorders caused by anxiety
- Premenstrual syndrome
- Alcohol and nicotine withdrawal.
Country of Manufacture: Russia
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