Anastrozole [Arimidex] [pharmacy] 1mg 30 tabs (30mg)

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Are you sure that you need Anastrozole (Arimidex)?

One colossal mistake widespread among bodybuilders and recreational enhanced lifters is that they have a predetermined dosage set for their Aromatase Inhibitor (AI).

It seems that AI usage has become so commonplace that users don’t even bother to understand the purpose of the drug in the first place prior to implementing it into their regimen.

Nowadays, AI’s are treated almost as on-cycle essentials, and are simply a necessity just like your multivitamin you pop each day is.

This couldn’t be further from the truth, and it explains why many individuals embark on their anabolic cycles with a misconception that they need an AI in there at a particular dosage to “prevent side effects.”

Typically, most men feel their best when their estrogen levels lie between 20-30 pg/ml in their blood work.

When you are utilizing a drug that aromatizes into Estrogen and an AI may become necessary, you get baseline blood work, and then when you add an AI in, you use a very conservative dose of the most mild and forgiving AI there is (depending on what/how much aromatizing hormones you’re using), and titrate up accordingly based on your blood work until you’ve reached the Estrogen sweet spot (or based on symptoms which is the “bro” method which is not recommended).

The goal you should have is to keep your Estrogen between 20-30 pg/ml for the entirety of your cycle, regardless of what dosage of AI is necessary to achieve that.

This is the target “estrogen sweet spot” you want to shoot for to feel amazing and improve your quality of life substantially.

If you start to get too far above this level, you can start to experience symptoms of high Estrogen.

If you start to get too far below this level, you can start to experience symptoms of low Estrogen.

Both scenarios are very unpleasant to say the least.

So, the key to staying in the sweet spot is getting your blood work done, and adjusting your AI dose accordingly based upon your current Aromatase Inhibitor needs.

If your Estrogen is too high, then you need to slightly increase your AI dose, or switch to a stronger one and start the titration process over again.

If your Estrogen is too low, then you need to slightly lower your AI dose, or switch to a weaker one and start the titration process over again.

Which Aromatase Inhibitor you should choose and the dosage you use should be based on your own individual propensity to aromatization, what your blood work indicates, the dosage of the aromatizing drugs you are using, etc.

Which Aromatase Inhibitor Is Weakest And Which Is The Strongest

• Arimistane (greatest margin of error, weakest aromatase inhibitor)
• Exemestane (Aromasin) (high margin of error, fairly strong aromatase inhibitor)
• Anastrozole (Arimidex) (low margin of error, fairly easy to crash Estrogen unless on a high dose of aromatizing compounds, very strong aromatase inhibitor)
• Letrozole (minimal margin of error, VERY easy to crash Estrogen by accident, even on tons of aromatizing compounds, the strongest aromatase inhibitor)

Overview of Anastrozole (Arimidex)

Anastrozole (Arimidex) belongs to a category and class of drugs known as aromatase inhibitors (AIs). Aromatase inhibitors belong to an even broader class of drugs known as anti-estrogens. The other subcategory of drug under the anti-estrogens category is known as selective estrogen receptor modulators (SERMs), such as Tamoxifen (Nolvadex) and Clomifene (Clomid). AIs and SERMs make up anti-estrogens. Aromatase inhibitors differ greatly from SERMs in their action and how they deal with the issues of estrogen control. The misunderstanding that SERMs, such as Nolvadex and Clomid, serve to lower estrogen levels must first be addressed. This is a persistent rumor among the anabolic steroid using community that has begun to erode as of late, but the rumor still persists. SERMs serve to block the action of Estrogen at the receptor sites in breast tissue by occupying the receptor sites in place of Estrogen so that Estrogen itself cannot exert its effects there through receptor site binding. Conversely, SERMs will also act as Estrogens at receptor sites at other cells in other areas of the body (the liver, for example inTamoxifen’s case). SERMs do not lower circulating levels of Estrogen in blood plasma. Aromatase inhibitors serve to do this by eliminating the production of Estrogen through binding to and disabling the aromatase enzyme, which is the enzyme responsible for the conversion (or aromatization) of androgens into Estrogen.

Anastrozole is regarded as one of the newer aromatase inhibitors, known as a third generation aromatase inhibitor.

Because Anastrozole was the very first aromatase inhibitor for many bodybuilders to have taken notice of, it is the most popular aromatase inhibitor used among anabolic steroid users for the purpose of Estrogen control. The use among anabolic steroid using athletes is for the control of almost all Estrogen-related side effects: the manifestation of gynecomastia, water retention and bloating, rising blood pressure (as a result of water retention increases from Estrogen). This is in contrast with SERMs such as Tamoxifen (Nolvadex), which only serve to block gynecomastia.

Aside from the use in bodybuilders, Anastrozole has also been medically used in males as well. Some males exhibit abnormally high Estrogen levels of many different reasons and Anastrozole has been utilized in order to combat these ailments. In particular, Anastrozole has been used to treat male adolescents that exhibit excessive Estrogen levels during purberty, resulting in unwanted pubertal gynecomastia. In addition, excessive Estrogen levels in adolescent males during puberty can often result in stunted growth due to the fact that Estrogen plays a key role in fusing the growth plates of the bones shut, preventing any further linear growth, and Anastrozole has also been used to treat these conditions as well

Properties of Anastrozole (Arimidex)

Anastrozole’s effects on serum Estrogen level control can be quite drastic even at a dose of 1mg daily. The amount of Estrogen suppression resulting from this dose has been demonstrated to be over 80% in patients. Anastrozole can be so effective at inhibiting the aromatase enzyme and thereby reducing Estrogen levels that this compound is typically only administered to post-menopausal females, and/or utilized when other first-line treatments for breast cancer has failed.

Common symptoms of high estrogen include:

• Acne, oily skin
• Erectile dysfunction
• Low libido
• Lethargy
• Gynecomastia (man boobs)
• Aggression and bitchiness
• Depression
• Water retention
• High blood pressure
• Enlarged prostate
• Shrunken testicles
• Sugar cravings

Common symptoms of low estrogen include:

• Dull weak orgasms
• Dry skin and lips
• Dehydration
• Low libido
• Irritability
• Mood swings
• Loss of appetite
• Fatigue
• Lethargy

The goal you should have is to keep your Estrogen between 20-30 pg/ml for the entirety of your cycle, regardless of what dosage of AI is necessary to achieve that.

Bodybuilders and athletes utilizing anabolic steroids will usually favor aromatase inhibitors such as Anastrozole for its ability to eliminate rising Estrogen levels at its root cause: aromatase. By disabling the aromatase enzyme, supraphysiological levels of aromatizable androgens (such as Testosterone, Dianabol, Boldenone, etc.) cannot convert into Estrogen, thereby eliminating any possible risk of Estrogen-related side effects.

Anastrozole (Arimidex) Side Effects

Being that Anastrozole (Arimidex) is an ancillary compound for the purpose of Estrogen control within the body, it is a compound that is generally well tolerated by male users. There are, however, some Anastrozole side effects to be concerned about. This primarily exists in the form of excess reduction of blood plasma levels of Estrogen in the body, as well as long-term Estrogen suppression. Anastrozole does affect females in a far greater and significant manner than it does in male users as well.

Studies have demonstrated that Anastrozole use results in the increased incidence and probability of experiencing bone fractures. Although this is a more female-specific side effect of Anastrozole use, Estrogen does play an important role in the promotion and retention of bone mineral content in males as well. There have been studies conducted that discovered that Anastrozole does negatively impact calcium turnover levels in bone tissue with even short term use.

Lethargy and fatigue is commonly associated with Anastrozole use. As with nearly all Estrogen reduction compounds, a reduction in circulating Estrogen levels means that the important role that Estrogen plays in the CNS (Central Nervous System) is reduced, thus resulting in possible instances of chronic fatigue. This is usually the result of Estrogen levels being reduced to levels that are considered far too low to be healthy.

One particularly prominent side effect of Anastrozole use is the negative impact on blood cholesterol profiles. As with nearly all Estrogen reducing compounds, Arimidex will also decrease HDL (good) cholesterol and increase LDL (bad cholesterol). This is because Estrogen is responsible for the promotion of healthy cholesterol levels in the body, and a disruption of normal blood plasma levels of Estrogen will indeed throw that off.

One Anastrozole side effect of importance is the possibility of Estrogen rebound. This exists in particular with two of the three most popular aromatase inhibitors (Anastrozole and Letrozole). The third aromatase inhibitor, Aromasin (Exemestane) does not share this same attribute of the possibility of Estrogen rebound.

What this means for the end user is the risk of a rebound of Estrogen levels (and thus, Estrogen related side effects) if Anastrozole use is halted too soon or abruptly after beginning use.

Anastrozole For Gynecomastia and Estrogen Control On-Cycle

For the purpose of Gynecomastia control and general on-cycle Estrogen control, Anastrozole is to be used at a general range of 0.5 – 1mg per day, and can be adjusted depending on the user’s tolerance and reaction to the compound. Everyone should adjust their Anastrozole dosage according to their individual response. It is not uncommon for 0.5mg/day to even be too much (or too little) for some. It should also always be remembered that the purpose here is Estrogen control during a cycle, not total elimination of Estrogen levels.

Anastrozole For Post Cycle Therapy (PCT)

Anastrozole dosage of 0.5mg to 1mg per day (or after 1 day) should be sufficient for the duration of any PCT length.

The usage requirements of Aromatase Inhibitors while on SARMs will greatly differ from that of traditional aromatizing Steroids as well, which needs to be taken into consideration if that’s what you are using.

Anastrozole or Letrozole would be way overkill on a SARM cycle and would actually just cause more issues rather than help.

Low Estrogen side effects are just as bad as high Estrogen side effects.

The most common being Tamoxifen  (Nolvadex), and Clomifene (Clomid).

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