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NSI-189 Freebase 1g
Also, we have NSI-189 Phosphate powder.
NSI-189 Phosphate is better for oral dosing, where NSI-189 Freebase is better for the sublingual ROA
WHAT IS NSI-189 ?
NSI-189 is an experimental drug currently being developed and studied by Neuralstem Inc., a biotechnology company that commercially produces neural stem cells for therapy. The research and development of NSI-189 began in the 1990s, during the years of Bill Clinton’s presidency.
The Clinton administration contracted Neuralstem to research the possibilities of creating a “super soldier,” one that was able to stay awake and alert for extended periods of time. The researchers at Neuralstem recognized that a drug targeting the hippocampus could possibly alleviate the effects of sleep deprivation and exhaustion, and set out to find a drug that could induce neurogenesis. Neuralstem, finding their prospects to be promising, continued research in this vein even after the government program was canceled.
This preliminary research would eventually result in the drug NSI-189. Clinical research on NSI-189 has been in the works since 2011, and a phase 1b trial was completed in July of 2014. Clinical phase 1 trials typically focus on finding the correct dosage range of the drug, which has been placed around 40 to 80 mg per day in the treatment of Major Depressive Disorder (MDD) and cognitive decline.
As mentioned above, the potential benefits of NSI-189 are:
- Improvement in behavioral responses associated with depression.
- Reversal of hippocampal atrophy.
- May enhance memory and cognition through increase neurogenesis, particularly in depressed subjects.
- Positive effects may persist after treatment ceases.
40-120mg per day
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